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Was a pioneer preacher of Knox County, Indiana. He owned a farm, on which he resided, ten miles north of Vincennes. But much of his work was done in Illinois. Indeed, he was the Nestor of the Restoration movement from Hutsonville to Golconda. His home was at the former place for a time. His courageous and devoted labors laid the foundation for many congregations in that section.
In the forties, there were bands of outlaws that overran several counties in southern Illinois. An organization, styling themselves "Regulators," was formed to crush them. These soon became as lawless as the outlaws. Civil anarchy was rampant. Mr. Trimble continued his ministry in the midst of the violent disturbances, publicly denouncing the wrong-doers. On one occasion he was baptizing some converts in the Ohio River, when some of the outlaws made a murderous attack upon him. Mr. Trimble defended his life by resisting the assault to the utmost. When the encounter was over, two of the outlaws were wounded and one of them was not. Gradually the civil disturbance wore itself out and society returned its normal conditions. Through it all, Mr. Trimble preached the gospel of salvation and peace.